Practice effects predict cognitive outcome in amnestic mild cognitive impairment.
Am J Geriatr Psychiatry
; 19(11): 932-9, 2011 Nov.
Article
em En
| MEDLINE
| ID: mdl-22024617
ABSTRACT
OBJECTIVE:
Practice effects on cognitive tests have been shown to further characterize patients with amnestic mild cognitive impairment (aMCI) and may provide predictive information about cognitive change across time. We tested the hypothesis that a loss of practice effects would portend a worse prognosis in aMCI.DESIGN:
Longitudinal, observational design following participants across 1 year.SETTING:
Community-based cohort.PARTICIPANTS:
Three groups of older adults 1) cognitively intact (n = 57), 2) aMCI with large practice effects across 1 week (MCI + PE, n = 25), and 3) aMCI with minimal practice effects across 1 week (MCI - PE, n = 26). MEASUREMENTS Neuropsychological tests.RESULTS:
After controlling for age and baseline cognitive differences, the MCI - PE group performed significantly worse than the other groups after 1 year on measures of immediate memory, delayed memory, language, and overall cognition.CONCLUSIONS:
Although these results need to be replicated in larger samples, the loss of short-term practice effects portends a worse prognosis in patients with aMCI.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prática Psicológica
/
Desempenho Psicomotor
/
Disfunção Cognitiva
/
Amnésia
/
Testes Neuropsicológicos
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Geriatr Psychiatry
Assunto da revista:
GERIATRIA
/
PSIQUIATRIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos