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nardosinane-type sesquiterpenoids from the formosan soft coral Paralemnalia thyrsoides.
Huang, Chiung-Yao; Su, Jui-Hsin; Chen, Bo-Wei; Wen, Zhi-Hong; Hsu, Chi-Hsin; Dai, Chang-Feng; Sheu, Jyh-Horng; Sung, Ping-Jyun.
Afiliação
  • Huang CY; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
  • Su JH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
  • Chen BW; National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
  • Wen ZH; Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan.
  • Hsu CH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
  • Dai CF; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
  • Sheu JH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
  • Sung PJ; Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan.
Mar Drugs ; 9(9): 1543-1553, 2011.
Article em En | MEDLINE | ID: mdl-22131957
ABSTRACT
Five new nardosinane-type sesquiterpenoids, paralemnolins Q-U (1-5), along with three known compounds (6-8), were isolated from the Formosan soft coral Paralemnalia thyrsoides. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods, and the absolute configuration of 1 was determined by the application of Mosher's method on 1. Among these metabolites, 1 and 3 are rarely found nardosinane-type sesquiterpenoids, possessing novel polycyclic structures. Compounds 1, 3, 6 and 7 were found to possess neuroprotective activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Fármacos Neuroprotetores / Antozoários Limite: Animals / Humans Idioma: En Revista: Mar Drugs Assunto da revista: BIOLOGIA / FARMACOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Fármacos Neuroprotetores / Antozoários Limite: Animals / Humans Idioma: En Revista: Mar Drugs Assunto da revista: BIOLOGIA / FARMACOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Taiwan