[Effects of trophoblastic beta 1-glycoprotein (TBG) on the functional activity of different cell lines]. / Vliianie trofoblasticheskogo beta 1-glikoproteina (TBG) na funktsional'nuiu aktivnost' razlichnykh kletochnykh linii.
Biull Eksp Biol Med
; 110(7): 72-4, 1990 Jul.
Article
em Ru
| MEDLINE
| ID: mdl-2224110
ABSTRACT
The effect of TBG on the functional activity of different cell lines, spontaneous and Con A induced proliferation of PBL was studied. If concentration of TBG is higher than 50 mu kg/ml it suppresses the proliferation in many used cell lines, except choriocarcinoma and cancer of uterus. The reliable increasing of spontaneous proliferation of PBL, Jurkat and K-562 cells may be observed if concentration is more lower (0.5-15 mu kg/ml). However proliferation of other cell lines corresponds to control level, and Con A induced proliferation of PBL is inhibited. The effect was more marked at 48, as compared to 24 hours of cell incubation with TBG.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glicoproteínas beta 1 Específicas da Gravidez
/
Células Tumorais Cultivadas
/
Biomarcadores Tumorais
Limite:
Female
/
Humans
Idioma:
Ru
Revista:
Biull Eksp Biol Med
Ano de publicação:
1990
Tipo de documento:
Article