Two outbreaks of neuropathogenic equine herpesvirus type 1 with breed-dependent clinical signs.
Vet Rec
; 170(9): 227, 2012 Mar 03.
Article
em En
| MEDLINE
| ID: mdl-22262701
ABSTRACT
Equine herpesvirus type 1 (EHV-1) is a worldwide spread pathogen of horses. It can cause abortion, respiratory and neurological disease and consequentially significant economic losses in equine industries. During 2009, two outbreaks of EHV-1 were confirmed in two stud farms in Eastern Croatia. The first outbreak occurred in February following the import of 12 horses from USA, serologically negative to EHV-1 before transport. Four mares aborted in the late stage of pregnancy and one perinatal death was recorded. Other six mares showed clinical signs of myeloencephalopathy with fatal end in four. One month later, the second EHV-1 outbreak was confirmed in stud farm about 100 km further with 17 abortions, three perinatal deaths and one mild neurological case. Epidemiological data showed that the disease was probably introduced in the first stud farm during international transport. The second outbreak started with the introduction of clinically healthy stallion from the first stud farm. Molecular characterisation and phylogenetic analysis confirmed that, despite different clinical signs, the identical virus caused both outbreaks. Both horse populations were free from EHV-1 infection before the outbreak and had not been vaccinated. Significant difference in clinical signs could be explained by different breed-related risk factors.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Herpesvirus Equídeo 1
/
Infecções por Herpesviridae
/
Aborto Animal
/
Doenças dos Cavalos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Animals
/
Pregnancy
País/Região como assunto:
America do norte
/
Europa
Idioma:
En
Revista:
Vet Rec
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Croácia