CdSe and ZnSe quantum dots capped with PEA for screening C-reactive protein in human serum.
Talanta
; 93: 411-4, 2012 May 15.
Article
em En
| MEDLINE
| ID: mdl-22483930
ABSTRACT
A fluorescence chemical sensor for C-reactive protein (CRP) was developed based on the selective interaction with CdSe and ZnSe quantum dots (QDs) coated with O-phosphorylethanolamine (PEA). Synthesis procedure and analytical parameters such as pH and ionic strength were studied. The decrease in the fluorescence emission intensity was explained due to the specific interaction of the QDs-PEA with CRP, and a correlation was observed between the quenching of the fluorescence and the concentration of CRP. The accuracy of the proposed method was 0.37% as RSD. The proposed method was applied to screen serum samples, and showed to be sensible at the C-reactive protein concentrations of risks levels.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Análise Química do Sangue
/
Proteína C-Reativa
/
Compostos de Zinco
/
Compostos de Selênio
/
Compostos de Cádmio
/
Pontos Quânticos
/
Etanolaminas
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Talanta
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Portugal