Enthalpy of helix-coil transition of DNA: dependence on Na+ concentration and GC-content.
J Biomol Struct Dyn
; 8(1): 131-8, 1990 Aug.
Article
em En
| MEDLINE
| ID: mdl-2275791
ABSTRACT
The enthalpy of helix-coil transition of DNA (delta H) is determined from the experiments on DNA melting with ligands by means of absolutely general formula, which contains only values directly known from the experiment (M.D. Frank-Kamenetskii, and A.T. Karapetian, Mol. Biol. USSR 6, 621 (1972)) with the combination of the "area" method (P.O. Vardevanian, et al., Biophysica 28, 130 (1983)). The experimentally obtained data show that delta H depends on both concentration of Na+ in solution and GC-content of DNA and is of high accuracy.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sódio
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DNA Bacteriano
Idioma:
En
Revista:
J Biomol Struct Dyn
Ano de publicação:
1990
Tipo de documento:
Article