Characterizing the effect of heavy metal contamination on marine mussels using metabolomics.
Mar Pollut Bull
; 64(9): 1874-9, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-22770532
ABSTRACT
Marine mussels (Mytilus) are widely used as bioindicators to measure pollution in marine environments. In this study, (1)H NMR spectroscopy and multivariate statistical analyses were used to differentiate mussel groups from a heavy metal-polluted area (Onsan Bay) and a clean area (Dokdo area). Principal component analysis and orthogonal projection to latent structure-discriminant analysis revealed significant separation between extracts of mussels from Onsan Bay and from the Dokdo area. Organic osmolytes (betaine and taurine) and free amino acids (alanine, arginine, glutamine, phenylalanine, and threonine) were more highly accumulated in Onsan Bay mussels compared with Dokdo mussels. These results demonstrate that NMR-based metabolomics can be used as an efficient method for characterizing heavy metal contamination derived from polluted area compared to clean area and to identify metabolites related to environments that are contaminated with heavy metals.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
/
Monitoramento Ambiental
/
Metais Pesados
/
Mytilus
/
Metaboloma
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Mar Pollut Bull
Ano de publicação:
2012
Tipo de documento:
Article