Calcineurin/NFATc signaling: role in postnatal ß cell development and diabetes mellitus.
Dev Cell
; 23(1): 7-8, 2012 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-22814597
ABSTRACT
Pancreatic islets are aggregates of endocrine cells required for blood glucose control and diabetes prevention after birth. In this issue of Developmental Cell, Goodyer et al. (2012) reveal a function of calcineurin, a calcium-activated serine/threonine phosphatase, in postnatal NFATc-regulated expression of genes that help ß cells to form insulin-containing vesicles and enter the cell cycle.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Dev Cell
Assunto da revista:
EMBRIOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Alemanha