Gas chromatographic identification and quantification of hydroxyzine: application in a fatal self-poisoning.
Forensic Sci Int
; 48(2): 139-43, 1990 Dec.
Article
em En
| MEDLINE
| ID: mdl-2283137
ABSTRACT
A method for the identification and quantification of hydroxyzine in human fluids by GC/NPD is presented. The method employs acepromazine as the internal standard and requires no derivatization. After a single alkaline extraction in n-heptane isoamylalcohol (98.51.5, v/v), analysis is achieved in 7 min. The lower limit of detectability was 0.8 ng/ml in plasma. Capillary gas chromatography mass spectrometry assay was developed for confirmation. Toxicological findings, after a fatality involving hydroxyzine are presented as an application of the procedure.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Suicídio
/
Hidroxizina
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Forensic Sci Int
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
França