N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-4,4''-difluoro-5'-hy-droxy-1,1':3',1''-terphenyl-4'-carboxamide.
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 9): o2619-20, 2012 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-22969521
ABSTRACT
The asymmetric unit of the title compound, C(27)H(16)F(2)N(2)O(4), consists of two crystallographically independent mol-ecules (A and B). In mol-ecule B, the isoindoline-1,3-dione ring system is disordered over two set of sites with a site-occupancy ratio of 0.658â
(12)0.342â
(12). In mol-ecule A, the fluoro-substituted benzene rings make dihedral angles of 18.36â
(8) and 46.37â
(8)° with the central benzene ring, whereas the corresponding angles are 40.90â
(8) and 52.89â
(9)° in mol-ecule B. The isoindoline ring system in mol-ecule A and the major and minor components of the disordered isoindoline ring system in mol-ecule B make dihedral angles of 58.50â
(4), 54.13â
(16) and 70.01â
(28) °, respectively, with their attached benzene rings, linked through the amide group. An intra-molecular O-Hâ¯O hydrogen bond generates an S(6) ring in each mol-ecule. In the crystal, mol-ecules are linked by N-Hâ¯O, C-Hâ¯F and C-Hâ¯O hydrogen bonds into sheets lying parallel to the bc plane. The crystal studied was a non-merohedral twin with a refined twin component ratio of 0.9316â
(8)0.0684â
(8).
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MEDLINE
Idioma:
En
Revista:
Acta Crystallogr Sect E Struct Rep Online
Ano de publicação:
2012
Tipo de documento:
Article