Incorporation of penicillin-producing fungi into living materials to provide chemically active and antibiotic-releasing surfaces.
Angew Chem Int Ed Engl
; 51(45): 11293-6, 2012 Nov 05.
Article
em En
| MEDLINE
| ID: mdl-23044633
ABSTRACT
Living materials artificial biological niches are loaded with the penicillin-producing mold Penicillium chrysogenum. This living material consumes food through a nanoporous top layer and releases the antibiotic on-site. No reloading of the active compound is needed. Gram-positive bacteria were efficiently killed if nearby, whereas Gram-negative bacteria (control experiment, not sensitive to penicillin) were not affected.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicilinas
/
Penicillium
/
Fungos
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Suíça