Immunoexpression of type-1 adiponectin receptor in the human intestine.
Cesk Patol
; 48(3): 165-6, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-23057433
ABSTRACT
UNLABELLED Adiponectin is an important biomarker of metabolic syndrome that was recently identified in human breast milk. We demonstrate the presence of type-1 adiponectin receptor (adipoR1) by immunoperoxidase method in 21 bioptic specimens - duodenum (n = 6), terminal ileum (n = 7) and colon (n = 8) from 14 human subjects (6 females and 8 males aged 9 months-47 years). In all the samples, adipoR1 was detected. The positivity was observed in enterocytes and colonocytes as well as in lymphocytes in the submucosa and in the smooth muscle of the intestinal wall. Thus, adiponectin may influence intestinal physiology through its type-1 receptor. KEYWORDS adiponectin - adiponectin receptor - intestine - nutritional programming - breast milk.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA Mensageiro
/
Receptores de Adiponectina
Limite:
Humans
Idioma:
En
Revista:
Cesk Patol
Ano de publicação:
2012
Tipo de documento:
Article