Selecting SNPs for pharmacogenomic association study.
Int J Data Min Bioinform
; 6(5): 521-34, 2012.
Article
em En
| MEDLINE
| ID: mdl-23155780
ABSTRACT
SNP genotyping device is an essential tool in the upcoming era ofpersonal genome and personalised medicine. Human genome has more than 10 million SNPs whereas conventional SNP genotyping device can only hold 1 million SNPs. Thus, intelligent SNP contents selection is required to maximise the value of SNP genotyping device. Here, we developed a new selection algorithm and applied this method to design genotyping contents for cancerand pharmacogenomic association study. This approach significantly increased the product value when compared with contents of competitive SNP genotyping product.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Farmacogenética
/
Algoritmos
/
Genoma Humano
/
Polimorfismo de Nucleotídeo Único
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Int J Data Min Bioinform
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2012
Tipo de documento:
Article