Separation and study of the range of plasminogen isoforms in patients with prostate cancer.
Biochemistry (Mosc)
; 77(9): 1065-71, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-23157267
ABSTRACT
Using affinity chromatography, two-dimensional electrophoresis, and MALDI-TOF mass spectrometry, plasminogen isoforms were separated and identified in blood plasma. Healthy donors and patients with prostate cancer in various stages of development were included in the studied sample. With the development of prostate cancer, four additional specific plasminogen isoforms are registered in blood plasma; they are characterized by lower molecular weights and higher pI values compared to isoforms found in the control group.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasminogênio
/
Neoplasias da Próstata
Limite:
Aged
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Biochemistry (Mosc)
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Federação Russa
País de publicação:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA