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Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatment.
Ladas, S D; Kamberoglou, D; Karamanolis, G; Vlachogiannakos, J; Zouboulis-Vafiadis, I.
Afiliação
  • Ladas SD; Gastroenterology Division, First Department of Medicine - Propaedeutic, Medical School, Athens University, Laikon Hospital, Athens, Greece.
Aliment Pharmacol Ther ; 37(2): 169-73, 2013 Jan.
Article em En | MEDLINE | ID: mdl-23252775
BACKGROUND: Gastric phytobezoars represent the most common bezoars in patients with poor gastric motility. A variety of dissolution therapies and endoscopic fragmentation techniques have been evaluated as conservative treatment so as to avoid surgery. AIM: To investigate the effectiveness of Coca-Cola for gastric phytobezoars dissolution. METHODS: We performed a systematic search to identify publications on gastric phytobezoars to assess the efficacy of Coca-Cola as a dissolution therapy. Diospyrobezoars, formed after persimmon ingestion, are a distinct type of phytobezoars characterized by their hard consistency. Thus, these two subgroups of bezoars were compared in terms of successful dissolution. RESULTS: Over a 10-year period (2002-2012), 24 papers including 46 patients have been published. In 91.3% of the cases, phytobezoar resolution with Coca-Cola administration was successful, either as a single treatment (50%) or combined with further endoscopic techniques, whereas only 4 patients underwent surgery. Phytobezoars were more likely to dissolve after initial attempt with Coca-Cola compared with diospyrobezoars (60.6% vs. 23%, P = 0.022). CONCLUSIONS: Coca-Cola alone is effective in gastric phytobezoar dissolution in half of the cases and, combined with additional endoscopic methods, is successful in more than 90% of them.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estômago / Bezoares / Bebidas Gaseificadas / Lavagem Gástrica Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: Aliment Pharmacol Ther Assunto da revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Grécia País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estômago / Bezoares / Bebidas Gaseificadas / Lavagem Gástrica Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: Aliment Pharmacol Ther Assunto da revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Grécia País de publicação: Reino Unido