[A resected case of signet-ring cell carcinoma of the rectum].
Gan To Kagaku Ryoho
; 39(12): 2283-5, 2012 Nov.
Article
em Ja
| MEDLINE
| ID: mdl-23268051
ABSTRACT
Here, we present the case of a 76-year-old woman who consulted us in April 2010, following a positive fecal occult blood test, and was diagnosed with lower rectal cancer. Signet-ring cell carcinoma was diagnosed by histology. Because hydronephrosis of both sides was considered the cause of dissemination of the tumor, only chemotherapy was performed. After the eighth course of XELOX+bevacizumab treatment, hydronephrosis of both sides improved and the tumor marker level became normal. An abdominoperineal rectal resection was performed in February 2011. The results of pathological examination of the resected specimen showed complete response. After the operation, the tumor marker level was elevated, and recurrence in the pelvic cavity and multiple bone metastases were detected by positron emission tomography/ computed tomography. Chemotherapy has now been resumed. Signet-ring cell carcinoma is rare in colorectal cancer. The frequency of multiple organ metastases is high, and the growth rate of the tumor is also high. Poor prognosis compared to the usual colorectal cancer has been reported.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pélvicas
/
Neoplasias Retais
/
Neoplasias Ósseas
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Carcinoma de Células em Anel de Sinete
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Japão