Comparison of central venous catheter and peripheral vein samples of antibiotics in children with cystic fibrosis.
J Spec Pediatr Nurs
; 18(1): 33-41, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-23289453
ABSTRACT
PURPOSE. To determine if accurate serum antibiotic levels can be obtained from central venous catheters (CVCs) in pediatric patients with cystic fibrosis. DESIGN AND METHODS. Fifty paired CVC-peripheral vancomycin or tobramycin specimens were collected within 5 min of each other following a 5-ml flush and discard. Specimen samples were randomized by first site drawn. RESULTS. CVC-peripheral antibiotic levels were highly correlated (r =.97, p <.001), with no statistically significant difference (t = 1.18, p =.25). Bland-Altman plot analysis revealed a bias of.47, with limits of agreement ranging from -4.20 to 6.87. PRACTICE IMPLICATIONS. Accurate antibiotic concentrations can be obtained from CVCs, reducing pediatric patient trauma and stress.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tobramicina
/
Cateterismo Venoso Central
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Cateterismo Periférico
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Vancomicina
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Monitoramento de Medicamentos
/
Fibrose Cística
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Child
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Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Spec Pediatr Nurs
Assunto da revista:
ENFERMAGEM
/
PEDIATRIA
Ano de publicação:
2013
Tipo de documento:
Article