Comparisons of plasma and salivary cortisol determinations for the diagnostic efficacy of the dexamethasone suppression test.
Biol Psychiatry
; 27(8): 897-904, 1990 Apr 15.
Article
em En
| MEDLINE
| ID: mdl-2331497
ABSTRACT
The current status of the saliva dexamethasone suppression test (DST) is discussed and results from the literature reviewed. Evidence is presented that demonstrates that the efficacy of the salivary-based test is equal to that of the plasma DST provided that specifically developed radioimmunoassays are used for determination of salivary cortisol. Such evidence relied on measurement of cortisol in 300 matched samples of plasma and saliva provided by patients admitted to a routine psychiatric ward over a 2-year period. The results according to diagnosis (DSM-III categories) were in line with those generally reported. The influence of anticholinergic medication was examined this had no significant effects on the performance of the plasma or salivary-based DST.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Saliva
/
Dexametasona
/
Hidrocortisona
/
Transtorno Depressivo
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Biol Psychiatry
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Reino Unido