Identifying the perfusion deficit in acute stroke with resting-state functional magnetic resonance imaging.
Ann Neurol
; 73(1): 136-40, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-23378326
Temporal delay in blood oxygenation level-dependent (BOLD) signals may be sensitive to perfusion deficits in acute stroke. Resting-state functional magnetic resonance imaging (rsfMRI) was added to a standard stroke MRI protocol. We calculated the time delay between the BOLD signal at each voxel and the whole-brain signal using time-lagged correlation and compared the results to mean transit time derived using bolus tracking. In all 11 patients, areas exhibiting significant delay in BOLD signal corresponded to areas of hypoperfusion identified by contrast-based perfusion MRI. Time delay analysis of rsfMRI provides information comparable to that of conventional perfusion MRI without the need for contrast agents.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Descanso
/
Imageamento por Ressonância Magnética
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Circulação Cerebrovascular
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Acidente Vascular Cerebral
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Ann Neurol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Alemanha
País de publicação:
Estados Unidos