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Toxicological evaluation of pure hydroxytyrosol.
Auñon-Calles, David; Canut, Lourdes; Visioli, Francesco.
Afiliação
  • Auñon-Calles D; Seprox Biotech, Madrid, Spain; Harlan Laboratories S.A., Barcelona, Spain.
Food Chem Toxicol ; 55: 498-504, 2013 May.
Article em En | MEDLINE | ID: mdl-23380205
Of all the phenolic constituents of olives and extra virgin olive oil, hydroxytyrosol is currently being actively exploited as a potential supplement or preservative to be employed in the nutraceutical, cosmeceutical, and food industry. In terms of safety profile, hydroxytyrosol has only been investigated as the predominant part of raw olive mill waste water extracts, due to the previous unavailability of appropriate quantities of the pure compound. We report the toxicological evaluation of hydroxytyrosol and, based on the results, propose a No Observed Adverse Effects Level (NOAEL) of 500mg/kg/d.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Álcool Feniletílico Limite: Animals Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Espanha País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Álcool Feniletílico Limite: Animals Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Espanha País de publicação: Reino Unido