Synthesis and biological activity of a new frog skin peptide, ranamargarin.
Sci China B
; 33(2): 170-7, 1990 Feb.
Article
em En
| MEDLINE
| ID: mdl-2340087
ABSTRACT
A new frog skin peptide, ranamargarin depicted as H-Asp-Asp-Ala-Ser-Asp-Arg-Ala-Lys-Lys-Phe-Tyr-Gly-Leu-Met-NH2' was synthesized by the conventional method. Comparisons of chemical and biological properties of both the synthetic and natural ranamargarins indicated that they were identical, so the chemical structure of ranamargarin was confirmed. Preliminary pharmacological study showed that ranamargarin was highly selective towards the SP-P subtype receptor.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Taquicininas
/
Contração Muscular
/
Músculo Liso
Limite:
Animals
Idioma:
En
Revista:
Sci China B
Assunto da revista:
BIOLOGIA
/
CIENCIA
/
QUIMICA
Ano de publicação:
1990
Tipo de documento:
Article