Gene therapy for vein graft failure.
J Card Surg
; 28(2): 144-7, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23414326
ABSTRACT
The main pathologenesis of vein graft restenosis is neointimal hyperplasia associated with vascular smooth muscle cell migration and proliferation. Gene therapy offers a novel treatment method for reducing or delaying early thrombosis, intimal hyperplasia, and late atherosclerosis. In this review, we will (1) describe sequential pathologies of vein graft disease; (2) summarize the applications of gene therapy in vein graft restenosis; and (3) discuss novel gene therapy for vein graft failure.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Veia Safena
/
Terapia Genética
/
Ponte de Artéria Coronária
/
Reestenose Coronária
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
J Card Surg
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2013
Tipo de documento:
Article