[Surveillance of carbapenem-resistant enterobacteria in stool cultures in a university hospital in Santiago, Chile]. / Vigilancia de enterobacterias productoras de carbapenemasas en cultivos rectales en un hospital universitario de Santiago, Chile.
Rev Chilena Infectol
; 30(1): 103-6, 2013 Feb.
Article
em Es
| MEDLINE
| ID: mdl-23450421
ABSTRACT
BACKGROUND:
Clinical cultures detect only one-third of colonized patients with carbapenem-resistant Enterobacteriaceae. Early identification and contact precautions implementation would help to interrupt transmission. In our hospital no carbapenemase-producing enterobacteria infections have been described.AIM:
To perform stool surveillance cultures in patients hospitalized in critical care unit with the purpose to detect carbapenemase-producing Enterobacteriacea. MATERIAL ANDMETHODS:
Rectal swabs were obtained of patients after five or more days of hospital stay, on a monthly basis from July to December 2011. Phenotypic assays (modified test Hodge and phenylboronic acid test) and polymerase chain reaction (PCR) searching for six carbapenemases of group A and B of Ambler's classification were performed.RESULTS:
During this period, 241 surveillance rectal cultures were performed. Thirty eight enterobacteria isolated from 30 patients presented a decreased susceptibility to carbapenems by agar dilution method. All PCR were negative.CONCLUSION:
We found that despite the significant number of resistant isolates, patients hospitalized in our institution are not colonized with carbapenemase-producing Enterobacteriaceae. We highlight the importance of screening before having the problem in place.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carbapenêmicos
/
Infecção Hospitalar
/
Enterobacteriaceae
/
Infecções por Enterobacteriaceae
/
Fezes
/
Antibacterianos
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Humans
País/Região como assunto:
America do sul
/
Chile
Idioma:
Es
Revista:
Rev Chilena Infectol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Chile