A young male adolescent with feminine appearance: diagnosis of 46, XX syndrome neglected for 4 years with gynaecomastia presentation.
Andrologia
; 46(3): 325-8, 2014 Apr.
Article
em En
| MEDLINE
| ID: mdl-23488913
ABSTRACT
Gynaecomastia is common in infancy and adolescent boys, but other inciting causes should be kept in mind and necessitate further evaluation should be conducted to determine any underlying conditions. A 22-year-old unmarried male adolescent visited our endocrinology clinic for feminine appearance despite operations for bilateral gynaecomastia 4 years ago. Physical examination showed inverted triangular distribution of pubic hair, sparse beard, small-sized testes, flaccid short penis and surgical scar of the chest wall. Serum hormones study revealed primary hypergonadotropic hypogonadism, and cytogenetic study disclosed female complement (46, XX). The authors recommend that sexual chromosome abnormality should be considered in patients with hypogonadism to avert androgen deficiency-related complications early and that long-term team care should be provided to improve the patient's health-related quality of life.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Testiculares 46, XX do Desenvolvimento Sexual
/
Ginecomastia
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Hipogonadismo
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Aspecto:
Patient_preference
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Andrologia
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Taiwan