Ocular hypertension and the risk of blindness.
J Glaucoma
; 24(1): 9-11, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-23524855
ABSTRACT
PURPOSE:
To estimate the risk of blindness in patients with ocular hypertension (OHT) using an appropriate model and current empirical data.DESIGN:
A Markov model with data from a systematic literature review.METHODS:
A Markov model with 3 health states was built OHT, primary open-angle glaucoma (POAG), and unilateral blindness. Literature was searched for reports on conversion from OHT to POAG and progression from POAG to blindness, to estimate a range of annual conversion and progression probabilities. The model had a cycle length of 1 year.RESULTS:
The 15-year risk estimates ranged from 3.1% to 9.4% in untreated, and from 0.9% to 8.6% in treated patients with OHT. The ranges were the result of differences in patient populations, treatments, and outcome definitions in currently available empirical data.CONCLUSIONS:
The best estimates of the 15-year risk of unilateral blindness in patients with OHT, based on the currently available empirical data and an appropriate model, show that the risk is <10%.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipertensão Ocular
/
Cegueira
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Health_economic_evaluation
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
J Glaucoma
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Holanda