Preparation and antimalarial activity of semisynthetic lycorenine derivatives.
Eur J Med Chem
; 63: 722-30, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23567962
ABSTRACT
A set of twenty one lycorenine derivatives has been prepared from the alkaloid hippeastrine (1). The modifications performed on hippeastrine included some functional group transformations, structural simplification and preparation of dimers. All alkaloids were tested as potential antimalarial agents, being the hippeastrine dimers the most active compounds.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium falciparum
/
Alcaloides de Amaryllidaceae
/
Antimaláricos
Limite:
Humans
Idioma:
En
Revista:
Eur J Med Chem
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Espanha