Aberrant CD200/CD200R1 expression contributes to painful synovium hyperplasia in a patient with primary hypertrophic osteoarthropathy.
Rheumatol Int
; 33(10): 2509-12, 2013 Oct.
Article
em En
| MEDLINE
| ID: mdl-23595568
ABSTRACT
We present a case of hypertrophic osteoarthropathy (PHO), with painful synovium hyperplasia involving both knees that was refractory to corticosteroid treatment. His rheumatoid factor and anti-CCP antibody was negative, and his serum ESR and CRP level was within normal range. Histological examination of the synovium obtained from his right knee revealed endothelial hyperplasia and vascular thickening without inflammation that was in association with aberrant expression of CD200/CD200R1, which highlighted the importance of aberrant CD200/CD200R1 in the regulation of the endothelial activation that contributed to the development of synovium hyperplasia in this PHO patient.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteoartropatia Hipertrófica Primária
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Dor
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Membrana Sinovial
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Antígenos CD
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Receptores de Superfície Celular
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Antígenos de Superfície
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Rheumatol Int
Ano de publicação:
2013
Tipo de documento:
Article
País de publicação:
ALEMANHA
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ALEMANIA
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DE
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DEUSTCHLAND
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GERMANY