Clinical consequences of altered chemoreflex control.
Respir Physiol Neurobiol
; 189(2): 354-63, 2013 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-23681082
ABSTRACT
Control of ventilation dictates various breathing patterns. The respiratory control system consists of a central pattern generator and several feedback mechanisms that act to maintain ventilation at optimal levels. The concept of loop gain has been employed to describe its stability and variability. Synthesizing all interactions under a general model that could account for every behavior has been challenging. Recent insight into the importance of these feedback systems may unveil therapeutic strategies for common ventilatory disturbances. In this review we will address the major mechanisms that have been proposed as mediators of some of the breathing patterns in health and disease that have raised controversies and discussion on ventilatory control over the years.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mecânica Respiratória
/
Células Quimiorreceptoras
/
Hipercapnia
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Respir Physiol Neurobiol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos