Influenza virus A(H3N2) strain isolated from cerebrospinal fluid from a patient presenting myelopathy post infectious.
J Clin Virol
; 58(1): 283-5, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23809474
ABSTRACT
BACKGROUND:
Neurological involvement during influenza infection has been described during epidemics and is often consistent with serious sequelae or death.OBJECTIVE:
To investigate the etiologic agent involved in myelopathy post influenza-like syndrome. STUDYDESIGN:
This investigation focuses on virus isolation from the cerebrospinal fluid (CSF) collected from a 19-year-old male student presenting with clinical diagnosis of myelopathy post influenza-like syndrome. To achieve this goal, different cell cultures and molecular methodologies were carried out.RESULTS:
Influenza virus A(H3N2) strain was isolated in MDCK cell culture; virus particles were observed under electron microscopy. Phylogenetics analyses showed that the Brazilian influenza A(H3N2) strains were closely related to the A/Perth/16/2009-like.CONCLUSION:
This study demonstrates that influenza virus A(H3N2) strain was the cause of illness of the students. According to the Brazilian influenza virus sentinel surveillance data A/Perth/16/2009-LIKE (H3N2) strain has predominated during the 2010 influenza virus season in Brasília-DF.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças da Medula Espinal
/
Líquido Cefalorraquidiano
/
Influenza Humana
/
Vírus da Influenza A Subtipo H3N2
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Animals
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
J Clin Virol
Assunto da revista:
VIROLOGIA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Brasil