Baclofen in the treatment of persistent hiccup: a case series.
Int J Clin Pract
; 67(9): 918-21, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23834241
ABSTRACT
BACKGROUND:
Persistent hiccup is a worrying symptom both for patients, because of reduced quality of life, and for physicians, because of frustration for unsuccessful treatments.AIM:
To test baclofen administration for the treatment of persistent hiccup.METHOD:
We report a series of seven patients affected by persistent hiccup successfully treated with baclofen.RESULTS:
Hiccup stopped in all patients after a single administration of the drug.CONCLUSIONS:
Baclofen is a GABA(B) receptor agonist. It is conceivable that the reduction of dopamine release by GABA(B) receptor stimulation is able to interrupt hiccup's reflex arc.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Baclofeno
/
Agonistas dos Receptores de GABA-B
/
Soluço
/
Relaxantes Musculares Centrais
Aspecto:
Patient_preference
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Clin Pract
Assunto da revista:
MEDICINA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Itália