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Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
Holmes, Michael V; Simon, Tabassome; Exeter, Holly J; Folkersen, Lasse; Asselbergs, Folkert W; Guardiola, Montse; Cooper, Jackie A; Palmen, Jutta; Hubacek, Jaroslav A; Carruthers, Kathryn F; Horne, Benjamin D; Brunisholz, Kimberly D; Mega, Jessica L; van Iperen, Erik P A; Li, Mingyao; Leusink, Maarten; Trompet, Stella; Verschuren, Jeffrey J W; Hovingh, G Kees; Dehghan, Abbas; Nelson, Christopher P; Kotti, Salma; Danchin, Nicolas; Scholz, Markus; Haase, Christiane L; Rothenbacher, Dietrich; Swerdlow, Daniel I; Kuchenbaecker, Karoline B; Staines-Urias, Eleonora; Goel, Anuj; van 't Hooft, Ferdinand; Gertow, Karl; de Faire, Ulf; Panayiotou, Andrie G; Tremoli, Elena; Baldassarre, Damiano; Veglia, Fabrizio; Holdt, Lesca M; Beutner, Frank; Gansevoort, Ron T; Navis, Gerjan J; Mateo Leach, Irene; Breitling, Lutz P; Brenner, Hermann; Thiery, Joachim; Dallmeier, Dhayana; Franco-Cereceda, Anders; Boer, Jolanda M A; Stephens, Jeffrey W; Hofker, Marten H.
Afiliação
  • Holmes MV; Faculty of Population Health Sciences, University College London, London, United Kingdom. Electronic address: mvholmes@gmail.com.
  • Simon T; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, Department of Clinical Pharmacology, URC-EST, Paris, France; Université Pierre et Marie Curie, Paris, France; INSERM, U 698, Paris, France.
  • Exeter HJ; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.
  • Folkersen L; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands; Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands.
  • Guardiola M; Unitat de Recerca en Lípids i Arteriosclerosi, IISPV, Universitat Rovira i Virgili, CIBERDEM, Reus, Spain.
  • Cooper JA; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.
  • Palmen J; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.
  • Hubacek JA; Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
  • Carruthers KF; Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
  • Horne BD; Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, Utah; Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
  • Brunisholz KD; Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, Utah.
  • Mega JL; TIMI Study Group, Divison of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, Massachusetts.
  • van Iperen EPA; Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • Li M; Department of Biostatistics & Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
  • Leusink M; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.
  • Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
  • Verschuren JJW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Hovingh GK; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • Dehghan A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands; Member of the Netherlands Consortium on Healthy Aging (NCHA), Leiden, the Netherlands.
  • Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom.
  • Kotti S; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, Department of Clinical Pharmacology, URC-EST, Paris, France.
  • Danchin N; Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Department of Cardiology, Paris, France; Université Paris Descartes, Paris V, Paris, France.
  • Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany; LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
  • Haase CL; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Rothenbacher D; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany; Division of Clinical Epidemiology & Aging Research, German Cancer Research Center, Heidelberg, Germany.
  • Swerdlow DI; Faculty of Population Health Sciences, University College London, London, United Kingdom.
  • Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Staines-Urias E; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
  • van 't Hooft F; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Gertow K; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.
  • de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Panayiotou AG; Cyprus Cardiovascular Educational and Research Trust, Nicosia, Cyprus and Cyprus International Institute for Environmental and Public Health in association with the Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus.
  • Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Universitá di Milano, Milan, Italy; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
  • Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Universitá di Milano, Milan, Italy; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
  • Veglia F; Centro Cardiologico Monzino, IRCCS, Milan, Italy.
  • Holdt LM; LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, University Hospital Munich (LMU), Ludwig-
  • Beutner F; LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Department of Internal Medicine/Cardiology, Heart Center, University of Leipzig, Leipzig, Germany.
  • Gansevoort RT; University Medical Center Groningen, University of Groningen, Department of Internal Medicine, Groningen, the Netherlands.
  • Navis GJ; University Medical Center Groningen, University of Groningen, Department of Internal Medicine, Groningen, the Netherlands.
  • Mateo Leach I; University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, the Netherlands.
  • Breitling LP; Division of Clinical Epidemiology & Aging Research, German Cancer Research Center, Heidelberg, Germany.
  • Brenner H; Division of Clinical Epidemiology & Aging Research, German Cancer Research Center, Heidelberg, Germany.
  • Thiery J; LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.
  • Dallmeier D; Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany.
  • Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Boer JMA; Department for Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
  • Stephens JW; Diabetes Research Group, Institute of Life Sciences, College of Medicine, Swansea University, Swansea, Wales, United Kingdom.
  • Hofker MH; Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
J Am Coll Cardiol ; 62(21): 1966-1976, 2013 Nov 19.
Article em En | MEDLINE | ID: mdl-23916927
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Doenças Cardiovasculares / Regulação da Expressão Gênica / Fosfolipases A2 Secretórias / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Incidence_studies / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: J Am Coll Cardiol Ano de publicação: 2013 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Doenças Cardiovasculares / Regulação da Expressão Gênica / Fosfolipases A2 Secretórias / Análise da Randomização Mendeliana Tipo de estudo: Clinical_trials / Incidence_studies / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: J Am Coll Cardiol Ano de publicação: 2013 Tipo de documento: Article País de publicação: Estados Unidos