Changes in backscatter of liver tissue due to thermal coagulation induced by focused ultrasound.
J Acoust Soc Am
; 134(2): 1724-30, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23927213
ABSTRACT
Ultrasonic imaging has advantages in its self-consistency in guiding and monitoring ultrasonic treatment such as high-intensity focused ultrasound (HIFU) treatment. Changes in ultrasonic backscatter of tissues due to HIFU treatment have been observed, but their mechanism is still under discussion. In this paper, ultrasonic backscatter of excised and degassed porcine liver tissue was observed before and after HIFU exposure using a diagnostic scanner, and its acoustic impedance was mapped using an ultrasonic microscope. The histology of its pathological specimen was also observed using an optical microscope. The observed decrease in backscatter intensity due to HIFU exposure was consistent with a spatial Fourier analysis of the histology, which also showed changes due to the exposure. The observed increase in acoustic impedance due to the exposure was also consistent with the histological change assuming that the increase was primarily caused by the increase in the concentration of hepatic cells.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Som
/
Ultrassom
/
Eletrocoagulação
/
Ablação por Ultrassom Focalizado de Alta Intensidade
/
Fígado
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Acoust Soc Am
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Japão