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Fungal neuroinfections and fungaemia: unexpected increase of mortality from invasive fungal infections in 2005-2011 in comparison to 1989-1998: analysis of 210 cases.
Demitrovicova, Andrea; Liskova, Anna; Valach, Michal; Izakovic, Martin; Noge, Adriana; Baranova, Jana; Kalatova, Dagmar; Syrovatkova, Ludmila; Velicova, Jana; Bugykova, Beata; Gulasova, Ivica; Seinova, Dagmar; Mikolasova, Gertruda; Mutalova, Martina; Pilkova, Martina; Szabo, Ivan; Findova, Lubica; Madarasz, Istvan; Stanzyk, Martin; Mikulickova, Dagmar; Blazekova, Maria; Jankechova, Monika; Slezakova, Zuzana; Kuriplachova, Gabriela; Visnovsky, Jozef; Obrocnikova, Andrea; Blumm, Mathias; Blumm, Bernard; Wolfram, Simon; Zeleny, Peter; Otrubova, Jana; Rudinsky, Bruno; Nagyova, Zuzana; Vravcova, Martina; Kajaba, Jozef; Jexova, Sona; Oravec, Svetoslav; Toth, Slavomir; Klobucka, Stanislava; Gerigh, Jana; Schumann, Frank; Ambra, Robert; Bandura, Peter; Bonnack, Christian; Kubisova, Zuzana; Palo, Marek; Kalavsky, Erich; Drgona, Lubos; Mahesvaari, Rajoo; Riedl, Jan.
Afiliação
  • Demitrovicova A; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Liskova A; Nitra University Hospital, Department of Clinical Microbiology, Nitra, Slovakia.
  • Valach M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Izakovic M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Noge A; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Baranova J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Kalatova D; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Syrovatkova L; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Velicova J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Bugykova B; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Gulasova I; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Seinova D; National Cancer Institute and Medical School, Comenius University, Bratislava, Slovakia.
  • Mikolasova G; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Mutalova M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Pilkova M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Szabo I; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Findova L; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Madarasz I; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Stanzyk M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Mikulickova D; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Blazekova M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Jankechova M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Slezakova Z; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Kuriplachova G; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Visnovsky J; Jessenius Medical School, Martin, Slovakia.
  • Obrocnikova A; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Blumm M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Blumm B; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Wolfram S; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Zeleny P; St. John Neuman Institute, SEU, Pribram, Czech Republic.
  • Otrubova J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Rudinsky B; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Nagyova Z; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Vravcova M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Kajaba J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Jexova S; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Oravec S; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Toth S; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Klobucka S; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Gerigh J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Schumann F; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Ambra R; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Bandura P; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Bonnack C; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Kubisova Z; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Palo M; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Kalavsky E; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Drgona L; National Cancer Institute and Medical School, Comenius University, Bratislava, Slovakia.
  • Mahesvaari R; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
  • Riedl J; St. Elizabeth University, Institute of Tropical Medicine and PhD program, Bratislava, Slovakia.
Neuro Endocrinol Lett ; 34(Suppl 1): 32-5, 2013 Sep.
Article em En | MEDLINE | ID: mdl-24013604
ABSTRACT

OBJECTIVE:

In this short communication we compared the data of fungaemia cases in Slovak hospitals from 1989-1998 published in 1999-2000 with data from 2005-2011.

METHODS:

Risk factors, etiology and outcome of fungaemia between two periods (1989-1998 vs. 2005-2011) were compared and risk factors for death assessed by univariate analysis (CDC 2006 Statistical Package).

RESULTS:

In comparison to 1989-1998 when only amphotericin B and fluconazole has been used (55%), in 2005-2011 only 35.2% patients received FLU, but 26.4% received voriconazole, 22% caspofungin and anidulafungin and about 6.6% lipid formulations of Amphotericin B. In etiology, while in 1989-1998 only 37.1% (115/310) represented non-albicans Candida (NAC) and non-Candida yeasts in 2005-2011 already reached 63.7%. The significant increase of breakthrough fungaemia may be a sign of inappropriate empiric therapy.
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Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Neuro Endocrinol Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Eslováquia
Buscar no Google
Adicionar na Minha BVS
Imprimir
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PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Neuro Endocrinol Lett Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Eslováquia