New insights of Microsporidial infection among asymptomatic aboriginal population in Malaysia.
PLoS One
; 8(8): e71870, 2013.
Article
em En
| MEDLINE
| ID: mdl-24014078
ABSTRACT
BACKGROUND:
Studies on microsporidial infection mostly focus on immunodeficiency or immunosuppressive individuals. Therefore, this cross-sectional study describes the prevalence and risk factors of microsporidiosis among asymptomatic individuals in Malaysia. METHODS/FINDINGS:
Four hundred and forty seven stool samples were collected and examined for microsporidia after staining with Gram-chromotrope Kinyoun. Demographic, socioeconomic, environmental, and behavioral information were collected by using a pre-tested questionnaire. Overall, 67 (15%) samples were positive for microsporidia. The prevalence of infection was significantly higher among individuals aged more than 15 years compared to those aged <15 years (ORâ=â1.97, 95% CIâ=â1.08, 3.62; Pâ=â0.028). Furthermore, logistic regression analysis confirmed that the presence of other family members infected with microsporidia (ORâ=â8.45; 95% CIâ=â4.30, 16.62; P<0.001) and being a consumer of raw vegetables (ORâ=â2.05; 95% CIâ=â1.15, 3.66; Pâ=â0.016) were the significant risk factors of this infection.CONCLUSIONS:
These findings clearly show that exposure to microsporidia is common among Aboriginal population. Further studies using molecular approach on microsporidia isolates from asymptomatic individuals is needed to determine species-specific. The risk factors associated with microsporidiosis will help in identifying more clearly the sources of the infection in the environment that pose a risk for transmission so that preventive strategies can be implemented.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microsporidiose
/
Infecções Assintomáticas
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
PLoS One
Assunto da revista:
CIENCIA
/
MEDICINA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Malásia