Endogenous regulation of visceral pain via production of opioids by colitogenic CD4(+) T cells in mice.

Boué, Jérôme; Basso, Lilian; Cenac, Nicolas; Blanpied, Catherine; Rolli-Derkinderen, Malvyne; Neunlist, Michel; Vergnolle, Nathalie; Dietrich, Gilles

Boué, Jérôme; Basso, Lilian; Cenac, Nicolas; Blanpied, Catherine; Rolli-Derkinderen, Malvyne; Neunlist, Michel; Vergnolle, Nathalie; Dietrich, Gilles.

Afiliação

Boué J; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France.
Basso L; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France.
Cenac N; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France.
Blanpied C; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France.
Rolli-Derkinderen M; INSERM Unité 913, Nantes, France; Institut des Maladies de l'Appareil Digestif, Université de Nantes, Nantes, France.
Neunlist M; INSERM Unité 913, Nantes, France; Institut des Maladies de l'Appareil Digestif, Université de Nantes, Nantes, France.
Vergnolle N; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France; Department of Pharmacology and Physiology, University of Calgary, Calgary, Alberta, Canada.
Dietrich G; INSERM Unité 1043, Toulouse, France; CNRS, U5282, Toulouse, France; Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse UPS, Toulouse, France. Electronic address: gilles.dietrich@inserm.fr.

Gastroenterology ; 146(1): 166-75, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24055279

Assuntos

Colite/imunologia; Colo/imunologia; Plexo Mientérico/imunologia; Peptídeos Opioides/imunologia; Células Th1/imunologia; Células Th17/imunologia; Dor Visceral/imunologia; Animais; Colite/induzido quimicamente; Colite/patologia; Colo/inervação; Colo/patologia; Sulfato de Dextrana/efeitos adversos; Modelos Animais de Doenças; Imunidade nas Mucosas; Camundongos; Camundongos Endogâmicos BALB C; Camundongos SCID; Plexo Mientérico/fisiologia; Peptídeos Opioides/fisiologia

Palavras-chave

4',6-diamidino-2-phenylindole; CBA; Cytometric Bead Array; DAPI; DSS; FCS; HPRT; IBD; IFN; IL; Ig; Mouse Model; Mucosal Immunity; OVA; PBS; PDYN; PENK; POMC; T-helper; Th; UC; Visceral Sensitivity; dextran sulfate sodium; fetal calf serum; hypoxanthine phosphoribosyltransferase; immunoglobulin; inflammatory bowel disease; interferon; interleukin; mAb; mRNA; messenger RNA; monoclonal antibody; ovalbumin; phosphate-buffered saline; prodynorphin; proenkephalin; proopiomelanocortin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Colo / Células Th1 / Peptídeos Opioides / Células Th17 / Dor Visceral / Plexo Mientérico Limite: Animals Idioma: En Revista: Gastroenterology Ano de publicação: 2014 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos

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