Short synthesis of 3-(hydroxymethyl)xylitol and structure revision of the anti-diabetic natural product from Casearia esculenta.
Org Lett
; 15(21): 5610-2, 2013 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-24125121
3-(Hydroxymethyl)xylitol, a compound reportedly isolated from the root of Casearia esculenta (Roxb.), along with its three possible stereoisomers, has been synthesized for the first time by way of a triple dihydroxylation reaction performed upon the simplest cross-conjugated hydrocarbon, [3]dendralene. The data for the natural product do not match any of the isomeric 3-(hydroxymethyl)pentitols. The structure of the natural product from the root of Casearia esculenta (Roxb.) has been corrected by reanalysis of the published data.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Xilitol
/
Extratos Vegetais
/
Raízes de Plantas
/
Casearia
/
Diabetes Mellitus Experimental
/
Hipoglicemiantes
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Austrália
País de publicação:
Estados Unidos