Evaluation of hypoglycemic activity of total lignans from Fructus Arctii in the spontaneously diabetic Goto-Kakizaki rats.

Xu, Zhaohui; Ju, Jiaxing; Wang, Kai; Gu, Chenchen; Feng, Yi

Xu, Zhaohui; Ju, Jiaxing; Wang, Kai; Gu, Chenchen; Feng, Yi.

Afiliação

Xu Z; Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: zhhxu1970@gmail.com.
Ju J; Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wang K; Center for Drug Safety Evaluation, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Gu C; Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Feng Y; Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

J Ethnopharmacol ; 151(1): 548-55, 2014.

Article em En | MEDLINE | ID: mdl-24269245

Assuntos

Arctium/química; Diabetes Mellitus/tratamento farmacológico; Frutas/química; Lignanas/farmacologia; Animais; Glicemia/efeitos dos fármacos; Proteína C-Reativa/metabolismo; Ritmo Circadiano; Esquema de Medicação; Polipeptídeo Inibidor Gástrico/genética; Polipeptídeo Inibidor Gástrico/metabolismo; Regulação da Expressão Gênica; Peptídeo 1 Semelhante ao Glucagon/genética; Peptídeo 1 Semelhante ao Glucagon/metabolismo; Teste de Tolerância a Glucose; Insulina/sangue; Lignanas/química; Masculino; Ratos; Ratos Wistar

Palavras-chave

CHOL; DM; Diabetes; ELISA; FBG; Fructus Arctii; GIP; GK rats; GLP-1; Goto-Kakizaki rats; HDL-C; Hypoglycemic activity; Insulin secretion; LDL-C; OGTT; PBG; TG; TLFA; cholesterol; diabetes mellitus; enzyme-linked immunosorbent assay; fasting blood glucose; glucagon-like peptide-1; glucose-dependent insulinotropic polypeptide; high density lipoprotein cholesterol; low density lipoprotein cholesterol; oral glucose tolerance test; postprandial blood glucose; total lignans from Fructus Arctii.; triglycerides

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lignanas / Arctium / Diabetes Mellitus / Frutas Limite: Animals Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2014 Tipo de documento: Article

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