Meaningful improvement in walking performance after Botulinum neurotoxin A (BoNT-A) in chronic spastic patients.
NeuroRehabilitation
; 34(1): 185-92, 2014.
Article
em En
| MEDLINE
| ID: mdl-24284465
ABSTRACT
BACKGROUND:
Botulinum neurotoxin A (BoNT-A) may reduce lower limb spasticity but its role in improving walking ability remains to be established.OBJECTIVE:
To investigate the efficacy of simultaneous BoNT-A injections into several targeted spastic muscles of different joints on gait speed and on functional gains in gait performance in chronic stroke and MS patients.METHODS:
Twenty patients affected by stroke or multiple sclerosis were tested before, one and three months after BoNT-A administration. Gait was evaluated by the 10 Meter Walk Test; patients were stratified into functional ambulation classes accordingly. Spasticity was assessed using the modified Ashworth Scale.RESULTS:
At final assessment, spasticity was reduced in hip adductors and ankle plantar-flexors, gait speed improved and, 1/3rd of patients transitioned to a higher ambulation class. The pre-post difference in Level of Spasticity of the hips was a predictor for an increase in gait speed.CONCLUSIONS:
A meaningful improvement in walking performance can be obtained in chronic spastic patients after BoNT-A injection into several muscles, specifically the hip adductors.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Caminhada
/
Toxinas Botulínicas Tipo A
/
Recuperação de Função Fisiológica
/
Marcha
/
Espasticidade Muscular
/
Fármacos Neuromusculares
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
NeuroRehabilitation
Assunto da revista:
NEUROLOGIA
/
REABILITACAO
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Itália