Virus-induced signaling influences endosome trafficking, virus entry, and replication.
Methods Enzymol
; 534: 65-76, 2014.
Article
em En
| MEDLINE
| ID: mdl-24359948
ABSTRACT
Viruses are obligate intracellular pathogens that interact with host cell machinery for enabling entry, replication, and spread. This chapter describes methods for studying the interaction of viruses with host cell signaling pathways and surface receptors during cellular infection, with an emphasis on protein kinases. We also describe how use of immunofluorescence confocal microscopy for imaging virus-host interactions provides a powerful approach for obtaining structural correlations that extend results of immunological and biochemical assays.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Endossomos
/
Vírus Sinciciais Respiratórios
/
Transdução de Sinais
/
Vírus da Influenza A Subtipo H1N1
/
Fibroblastos
Limite:
Animals
Idioma:
En
Revista:
Methods Enzymol
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Canadá