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Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1.
Lemke, J; von Karstedt, S; Abd El Hay, M; Conti, A; Arce, F; Montinaro, A; Papenfuss, K; El-Bahrawy, M A; Walczak, H.
Afiliação
  • Lemke J; 1] Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK [2] Clinic of General and Visceral Surgery, University of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
  • von Karstedt S; Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
  • Abd El Hay M; Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
  • Conti A; 1] Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK [2] Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
  • Arce F; Cancer Immunology Unit, University College London, 72 Huntley Street, London WC1E 6DD, UK.
  • Montinaro A; Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
  • Papenfuss K; Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
  • El-Bahrawy MA; Department of Histopathology, Imperial College London, Du Cane Road, London W12 0NN, UK.
  • Walczak H; Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.
Cell Death Differ ; 21(3): 491-502, 2014 Mar.
Article em En | MEDLINE | ID: mdl-24362439

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinase 9 Dependente de Ciclina / Ligante Indutor de Apoptose Relacionado a TNF / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD / Proteína de Sequência 1 de Leucemia de Células Mieloides Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinase 9 Dependente de Ciclina / Ligante Indutor de Apoptose Relacionado a TNF / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD / Proteína de Sequência 1 de Leucemia de Células Mieloides Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido