Post-transfusion hypertension and seizure in congenital hemolytic anemia: a case report and literature review.
J Trop Pediatr
; 60(3): 253-6, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-24473404
ABSTRACT
A rare syndrome of hypertension, seizures and intracranial bleed has been reported among patients with congenital hemolytic anemia who underwent multiple blood transfusions. We report this syndrome in a 12-year-old Malay girl with hemoglobin E-beta-thalassemia, who underwent intensive transfusion and subsequently had headache, visual loss, severe hypertension and seizures. A comprehensive literature review revealed 30 patients with this syndrome, of whom 15 had intracranial bleed and 12 among these 15 died. A less-intensive transfusion regimen among patients with chronic hemolytic anemia and prompt detection and management of hypertension may prevent this potentially fatal syndrome.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Convulsões
/
Talassemia
/
Reação Transfusional
/
Hipertensão
Tipo de estudo:
Etiology_studies
Limite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Trop Pediatr
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Malásia