Skin necrosis due to fluindione treatment: a rare but serious complication.
J Wound Care
; 23(2 Suppl): S16-9, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24526169
ABSTRACT
In the setting of protein C deficiency, skin necrosis, which occurs most often at the initial phase of oral anticoagulants therapy, is a rare side effect. Six cases have previously been reported in the literature. In this case report, we present a protein C deficient 42-year-old woman who was being treated for venous thrombosis. Five days after the initiation of oral anticoagulant treatment, she developed extensive skin necrosis on her left calf, followed by a painful leg ulcer. The pathogenesis underlying skin necrosis caused by anticoagulation therapy is still not clear. Despite only a few cases being reported in the literature, it is important to recognise this complication since adequate therapeutic approaches leading to a stable anticoagulation state may prevent it.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenindiona
/
Úlcera Cutânea
/
Anticoagulantes
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Wound Care
Assunto da revista:
ENFERMAGEM
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Marrocos