Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging.

Ale-Agha, Niloofar; Dyballa-Rukes, Nadine; Jakob, Sascha; Altschmied, Joachim; Haendeler, Judith

Ale-Agha, Niloofar; Dyballa-Rukes, Nadine; Jakob, Sascha; Altschmied, Joachim; Haendeler, Judith.

Afiliação

Ale-Agha N; IUF - Leibniz Research Institute for Environmental Medicine at the University of Duesseldorf gGmbH, 40225 Duesseldorf, Germany. Electronic address: Niloofar.Ale-Agha@uni-duesseldorf.de.
Dyballa-Rukes N; IUF - Leibniz Research Institute for Environmental Medicine at the University of Duesseldorf gGmbH, 40225 Duesseldorf, Germany. Electronic address: Nadine.Dyballa@uni-duesseldorf.de.
Jakob S; IUF - Leibniz Research Institute for Environmental Medicine at the University of Duesseldorf gGmbH, 40225 Duesseldorf, Germany. Electronic address: Sascha.Jakob@uni-duesseldorf.de.
Altschmied J; IUF - Leibniz Research Institute for Environmental Medicine at the University of Duesseldorf gGmbH, 40225 Duesseldorf, Germany. Electronic address: Joachim.Altschmied@uni-duesseldorf.de.
Haendeler J; Central Institute of Clinical Chemistry and Laboratory Medicine, University of Duesseldorf, Germany; IUF - Leibniz Research Institute for Environmental Medicine at the University of Duesseldorf gGmbH, 40225 Duesseldorf, Germany. Electronic address: juhae001@uni-duesseldorf.de.

Exp Gerontol ; 56: 189-93, 2014 Aug.

Article em En | MEDLINE | ID: mdl-24583100

Assuntos

Envelhecimento/metabolismo; Senescência Celular; Mitocôndrias/enzimologia; Telomerase/metabolismo; Telômero/metabolismo; Transporte Ativo do Núcleo Celular; Fatores Etários; Envelhecimento/genética; Animais; Domínio Catalítico; Humanos; Fosforilação; Transdução de Sinais; Telomerase/genética

Palavras-chave

Aging; Mitochondria; Nucleus; Senescence; Telomerase reverse transcriptase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Telômero / Senescência Celular / Telomerase / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Exp Gerontol Ano de publicação: 2014 Tipo de documento: Article

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