Corneal dystrophy in Friesian horses may represent a variant of pellucid marginal degeneration.
Vet Ophthalmol
; 17 Suppl 1: 186-94, 2014 Jul.
Article
em En
| MEDLINE
| ID: mdl-24602247
ABSTRACT
OBJECTIVE:
To describe the clinical presentation, treatment, and outcome of a corneal dystrophy in Friesian horses and to analyze affected horses' pedigrees to investigate its heritability. ANIMALS Nine Friesians with bilateral disease were identified. PROCEDURE Retrospective medical record review was used to identify Friesian horses exhibiting bilateral symmetric corneal lesions. Variables identified from medical records included patient sex and age at diagnosis; location, depth and size of corneal lesions; medical and surgical therapy instituted; and visual outcome. A four-generation pedigree for each included horse was used to construct a combined pedigree.RESULTS:
The nine included horses had an average age at diagnosis of the first eye of 10.7 years, with males (8/9) significantly more frequently affected than females (1/9), P = 0.012. Lesions were inferior and averaged 5 mm in diameter. Depth ranged from superficial facets to perforations, which developed in nine of 18 eyes. Eight of nine perforations were surgically repaired, with seven of eight repaired eyes visual at last follow-up. All nine eyes that had not perforated remained visual. All affected horses shared a common ancestor within six generations.CONCLUSIONS:
This form of corneal dystrophy in Friesian horses, characterized by bilateral symmetric stromal loss, appears to be progressive but responds well to surgical repair, occurs more frequently in males, may have a genetic component in Friesian horses, and may be a variant of pellucid marginal degeneration.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Distrofias Hereditárias da Córnea
/
Doenças dos Cavalos
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Vet Ophthalmol
Assunto da revista:
MEDICINA VETERINARIA
/
OFTALMOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos