A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process.

Stuart, Shawn D; Schauble, Alexandra; Gupta, Sunita; Kennedy, Adam D; Keppler, Brian R; Bingham, Paul M; Zachar, Zuzana

Stuart, Shawn D; Schauble, Alexandra; Gupta, Sunita; Kennedy, Adam D; Keppler, Brian R; Bingham, Paul M; Zachar, Zuzana.

Afiliação

Bingham PM; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA. paul.bingham@stonybrook.edu.

Cancer Metab ; 2(1): 4, 2014 Mar 10.

Article em En | MEDLINE | ID: mdl-24612826

Texto completo

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108059
https://dx.doi.org/10.1186/2049-3002-2-4

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancer Metab Ano de publicação: 2014 Tipo de documento: Article