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Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation.
Blackburn, Jessica S; Liu, Sali; Wilder, Jayme L; Dobrinski, Kimberly P; Lobbardi, Riadh; Moore, Finola E; Martinez, Sarah A; Chen, Eleanor Y; Lee, Charles; Langenau, David M.
Afiliação
  • Blackburn JS; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02138, USA.
  • Liu S; Northwestern University, Chicago, IL 60208, USA.
  • Wilder JL; Harvard Stem Cell Institute, Boston, MA 02138, USA.
  • Dobrinski KP; Center for Integrative Medicine, University of South Florida, Tampa, FL 33620, USA.
  • Lobbardi R; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02138, USA.
  • Moore FE; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02138, USA.
  • Martinez SA; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Chen EY; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02138, USA; Department of Pathology, University of Washington Medical Center, Seattle, WA 98195, USA.
  • Lee C; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA; Department of Graduate Studies, Seoul National University School of Medicine, Seoul 110-744, South Korea.
  • Langenau DM; Department of Pathology, Regenerative Medicine and Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Boston, MA 02138, USA. Electronic address: dlangenau@mgh.harvard.edu.
Cancer Cell ; 25(3): 366-78, 2014 Mar 17.
Article em En | MEDLINE | ID: mdl-24613413
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Complexos Multiproteicos / Proteínas Proto-Oncogênicas c-akt / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Serina-Treonina Quinases TOR / Evolução Clonal Limite: Animals / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Complexos Multiproteicos / Proteínas Proto-Oncogênicas c-akt / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Serina-Treonina Quinases TOR / Evolução Clonal Limite: Animals / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos