Effect of cycloheximide on the levels of nuclear HMG proteins in rat liver.
Biochem Int
; 17(6): 1151-5, 1988 Dec.
Article
em En
| MEDLINE
| ID: mdl-2469423
ABSTRACT
Within 30 minutes of administration of cycloheximide to rats, rRNA synthesis in isolated liver nuclei was inhibited by approximately 50%. The nuclear contents of high mobility group (HMG) proteins, including HMG 1, 2 and 14, were found to be decreased in parallel with the inhibition of RNA synthesis while the contents of the total cellular HMG proteins remained unchanged. The role of HMG proteins in the regulation of RNA synthesis is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Grupo de Alta Mobilidade
/
Cicloeximida
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
Biochem Int
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Japão