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Induced pluripotent stem cells in hematology: current and future applications.
Focosi, D; Amabile, G; Di Ruscio, A; Quaranta, P; Tenen, D G; Pistello, M.
Afiliação
  • Focosi D; Division of Transfusion Medicine and Transplant Biology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
  • Amabile G; 1] Harvard Medical School, Boston, MA, USA [2] Harvard Stem Cell Institute, Boston, MA, USA.
  • Di Ruscio A; 1] Harvard Medical School, Boston, MA, USA [2] Harvard Stem Cell Institute, Boston, MA, USA.
  • Quaranta P; Retrovirus Centre and Virology Section, Department of Translational Research, University of Pisa, Pisa, Italy.
  • Tenen DG; 1] Harvard Medical School, Boston, MA, USA [2] Cancer Science Institute, National University of Singapore, Singapore, Singapore.
  • Pistello M; Retrovirus Centre and Virology Section, Department of Translational Research, University of Pisa, Pisa, Italy.
Blood Cancer J ; 4: e211, 2014 May 09.
Article em En | MEDLINE | ID: mdl-24813079
ABSTRACT
Reprogramming somatic cells into induced pluripotent stem (iPS) cells is nowadays approaching effectiveness and clinical grade. Potential uses of this technology include predictive toxicology, drug screening, pathogenetic studies and transplantation. Here, we review the basis of current iPS cell technology and potential applications in hematology, ranging from disease modeling of congenital and acquired hemopathies to hematopoietic stem and other blood cell transplantation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Blood Cancer J Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Blood Cancer J Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Itália