The effect of diet-induced obesity on the inflammatory phenotype of non-adipose-resident macrophages in an in vivo model of gout.

Shaw, Odette M; Pool, Bregina; Dalbeth, Nicola; Harper, Jacquie L

Shaw, Odette M; Pool, Bregina; Dalbeth, Nicola; Harper, Jacquie L.

Afiliação

Shaw OM; Arthritis and Inflammation Group, Malaghan Institute of Medical Research, Wellington and Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Pool B; Arthritis and Inflammation Group, Malaghan Institute of Medical Research, Wellington and Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Dalbeth N; Arthritis and Inflammation Group, Malaghan Institute of Medical Research, Wellington and Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Harper JL; Arthritis and Inflammation Group, Malaghan Institute of Medical Research, Wellington and Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. jharper@malaghan.org.nz.

Rheumatology (Oxford) ; 53(10): 1901-5, 2014 Oct.

Article em En | MEDLINE | ID: mdl-24831058

Assuntos

Dieta Hiperlipídica; Gota/metabolismo; Macrófagos/metabolismo; Obesidade/metabolismo; Animais; Quimiocina CCL2/metabolismo; Quimiocinas/metabolismo; Modelos Animais de Doenças; Gota/complicações; Gota/patologia; Inflamação/metabolismo; Inflamação/patologia; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Macrófagos/patologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Obesidade/complicações; Obesidade/patologia

Palavras-chave

cytokines; gout; inflammation; metabolic syndrome; monocytes; neutrophils; obesity; resident macrophages

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Hiperlipídica / Gota / Macrófagos / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Reino Unido

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