[Evaluation of bone mineral density in children with sickle cell disease]. / Evaluación de la densidad mineral ósea en pacientes con enfermedad de células falciformes.
An Pediatr (Barc)
; 82(4): 216-21, 2015 Apr.
Article
em Es
| MEDLINE
| ID: mdl-24838044
ABSTRACT
OBJECTIVE:
To evaluate bone mineral density (BMD) in children with sickle cell disease (SCD) in the Community of Madrid. MATERIAL ANDMETHODS:
The BMD was estimated in 40 children with SCD, and with an age range between 3 and 16 years, using densitometry (DXA), as recommended by the International Society for Clinical Densitometry (ISCD).RESULTS:
The mean age at the time of the study was 7.97±3.95 years, the mean value of the DXA expressed in Z -score was -0.91±1.46 with a range of minimum values - 5.30 and 2.30 maximum. More than half (57.5%) of all the children had normal BMD (Z>-1), 25% had low BMD (Z between -1 and -2), and 17.5% showed an abnormal Z -score values of osteoporosis (Z -score<-2). The Pearson linear correlation was statistically significant between Z -score value and the haemoglobin level (r=0.368, p=.019), finding no correlation with the levels of 25 (OH) vitamin D.CONCLUSION:
Prospective studies are needed with a larger number of patients to understand the future implications of bone densitometry changes and associated risk factors.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Densidade Óssea
/
Anemia Falciforme
Tipo de estudo:
Observational_studies
/
Prevalence_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
An Pediatr (Barc)
Assunto da revista:
PEDIATRIA
Ano de publicação:
2015
Tipo de documento:
Article